METHOD FOR DIFFERENTIAL DIAGNOSTICS OF COURSE OF CHRONIC ACQUIRED TOXOPLASMOSIS

摘要

A method for differential diagnostics of course of chronic acquired toxoplasmosis includes determination in blood of levels of immunoglobulins of A, M, G classes. One calculates total immunoglobulins and ratio of IgG to Ig,A. One determines regularities of changes in the ratio of characteristics of cell immunity, in particular the level of CD3+-lymphocytes, CD4+-helpers, content of CD8+-immune-suppressor cells. One determines leukocytal index of intoxication (LII), immune-regulation index (IRI) and functional state of CNS by data of EES. At combination of low level (LII) with decreased characteristics for CD3+-lymphocytes and low immune-regulation index (IRI) with increased levels of total immunoglobulins and EEG changes in diencephalic-stem region one diagnoses medium-severe unfavorable course of chronic acquired toxoplasmosis. At absence of changes in immune status and substantial changes of reference characteristics in hemogram one diagnoses a cyclic, sub-cyclic course of disease.