MONOCLONAL ANTIBODY AGAINST CD44 THAT MEDIATES CYTOTOXICITY IN CANCER CELLS

摘要

The invention relates to humanized antibody that specifically binds the same epitope or epitopes of human CD44 as the isolated monoclonal antibody produced by the hybridoma cell line H460-16-2 having ATCC Accession No. PTA-4621. Also disclosed is a composition comprising a humanized antibody and having the effect in treating a human tumor.