IMPROVED PHARMACEUTICAL COMPOSITION COMPRISING A CALCIUM CHANNEL ANTAGONIST SUCH AS LERCANIDIPINE, PROCESS FOR THE PREPARATION THEREOF

摘要

The present invention relates to the formulation of solid dosage forms comprising a therapeutically effective amount of a dihydropyridine calcium channel antagonist such as Lercanidipine or salt thereof, in combination with colloidal silicon dioxide such as Aerosil to enhance bioavailability and improve solubility, and a process for the preparation thereof by wet granulation.