CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS AGAINST METABOLIC DISORDERS

摘要

Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R, R, R, E, T, n and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.