New polyethylene glycol, a stable alpha interference copolymer, represents a localized isomer

摘要

New Derivatives of PEG - interferon and is linked to the creation of a New interferon conjugated with polyethylene glycol, active, highly Purified, stable, the activity of interferon alpha, with low immunogenicity, Biological Action prolongedImproved pharmacokinetic parameters of the General formula: N - where you enter values from the 10000 m - 227; integer Z4; IFN - polypeptide with natural or recombinant IFN Alpha activity.Also related to drugs containing the Conjugate of the formula (i), with appropriate drugs to treat diseases, Viral Diseases, cancer and primary or secondary immunodeficiency, containing the requested conjugated Peg IFN and auxiliary components.