Application device alternating magnetic field for heating magnetic or magnetizable substances in biological tissue, in particular for thermotherapy using magnetic nanoparticles, having an applicator (1) oversized with polar magnetic yoke (2) and two shoes ( 7, 8), opposite each other and separated by a space (13) of exposure field in the magnetic yoke (2) and with two magnetic coils (9, 10) respectively assigned to a pole shoe (7, 8) with drive connected control large applicator for AC power with a certain amplitude, a certain frequency and a position given stage for generating an alternating magnetic field (12) which is widely homogeneous in space (13) exposure field and has a measured field strength, being able to locate the biological tissue to be exposed to the field, such as exposure target volume field in space (13) of exposure field, and can be especially positioning a patient with a body part to be exposed to the field, for example, diseased prostate (23), in space (13) of exposure field, characterized in space (13) of field exposure in the area around the biological tissue to be exposed to the field, as target volume exposure field, in particular on or in a patient in the area near the body part to be will expose the field, for example, a diseased prostate (23), is arranged a hub (19) field which concentrates the alternating magnetic field (12) of the applicator (1) large in the target volume and thus it increases locally, being the field concentrator a ferrite as a passive field concentrator, or being the field concentrator active hub (19) of field with at least one magnetic coil (20) and being oriented at least one magnetic coil (20 ) so that s field lines of the active hub (19) field and the applicator (1) large are located approximately in the same direction, and a control unit (35, 38) control field concentrator being provided, by which the at least one magnetic coil (20) is supplied with a synchronous alternating current with the same frequency and the same phase corresponding to the alternating current of the applicator (1) large.
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