Use of peptide inhibitors with cellular permeability of the JNK signal transduction pathway for the treatment of inflammatory, chronic or non-chronic digestive diseases

摘要

Use of a JNK inhibitor peptide consisting of an amino acid sequence according to SEQ ID NO: 2 or of a chimeric peptide consisting of a first domain and a second domain linked by a covalent link, the first domain comprising a traffic sequence and consisting of the second domain in a JNK inhibitory sequence according to SEQ ID NO: 2, where the first domain is attached to the C-terminal end of the second domain, to prepare a pharmaceutical composition for the treatment of chronic or non-chronic inflammatory digestive diseases in a subject .