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CELLULAR VESICLE CALLED ''EXOSOME'', PREPARATION AND USE THEREOF IN IMMUNE STIMULATION

机译:细胞囊被称为“外来体”,制备及其在免疫刺激中的使用

摘要

The subject of the invention is a new process for sensitizing antigen presenting cells, new means for implementing the process, and new membrane vesicles having an immunogenic power. The invention relates in particular to texosomes (vesicles derived from tumor cells) and dexosomes (vesicles derived from dendritic cells loaded or not with antigens), and their use for vectorization and presentation of antigens in vitro or in vivo as well as in methods or compositions for the treatment of cancers, infectious, parasitic or autoimmune diseases in particular.
机译:本发明的主题是用于使抗原呈递细胞致敏的新方法,用于实施该方法的新方法以及具有免疫原性的新膜囊泡。本发明尤其涉及纹理体(得自肿瘤细胞的囊泡)和葡糖体(得自负载或不装载抗原的树突细胞的囊泡),及其在体外或体内以及在方法或组合物中用于抗原的载体化和呈递的用途。特别是用于治疗癌症,传染病,寄生虫病或自身免疫性疾病。

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