AMINOLEVULINIC ACID PHOTODYNAMIC THERAPY FOR TREATING SEBACEOUS GLAND DISORDERS

摘要

Light treatments of sebaceous gland disorders with 5-aminolevulinic acid andphotodynamic therapy are disclosed. A preferred treatment includes topicalapplication of 5-aminolevulinic acid to the skin followed by light exposureswith repeated treatment at various intervals. At low doses of ALA andphotodynamic therapy (PDT) in single or multiple treatments, improvement inthe sebaceous gland disorder, e.g., acne, provides the discovery thatdiminishment in sebum secretion and the eradication of bacteria occurs. Athigh doses of ALA and a single high energy PDT treatment, permanent changes tothe sebaceous gland and sebum secretion have been discovered.