PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY

摘要

The present invention relates to a composition comprising an extract ofPseudolysimachion genus plant, and the catalpol derivatives isolated therefromhaving anti-inflammatory, antiallergic and anti-asthmatic activity. Theextractof Pseudolysimachion genus plantand the catalpol derivatives isolatedtherefrom shows potent suppressing effect on elevated IgE, IL-4 and IL- 13levels and eosinophilia in the plasma and BALF, and mucus overproduction inthe lung tissues in an OVA-induced asthmatic mouse model. Therefore, it can beused as the therapeutics or functional health food for treating and preventinginflammatory, allergic and asthmatic disease.