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PROTOZOAN STRAIN OF THE SPECIES LEISHMANIA INFANTUM OF REDUCED VIRULENCE AND USE THEREOF

机译:降低致病性的利什曼原虫种的原生动物株及其用途

摘要

The present invention relates to a protozoan strain of the family of the Trypanosomatidae the virulence of which is lower than that of the corresponding wild-type strain, characterized in that at least one copy of the SIR2 gene present in the genome of the strain is inactivated.
机译:本发明涉及一种锥虫科的原生动物菌株,其毒力低于相应的野生型菌株,其特征在于该菌株基因组中存在的至少一个SIR2基因拷贝被灭活。 。

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