CALCIUM PHOSPHATE/CALCIUM SILICATE CEMENT FOR BIOMEDICAL APPLICATIONS

摘要

The present invention relates to a calcium phosphate/calcium silicate cement that comprises a 10 to 90% by volume fraction of silicon-doped brushite (DCPD, CaHPO₄.2H₂O), a hydrated calcium silicate fraction (C-S-H) and a further fraction comprising hydroxyapatite. In addition, the invention relates to a method for preparing said cement and to the composite ceramic comprising beta tricalcium phosphate (Ca₃(PO₄)₂) doped with silicon and silicocarnotite (Ca₅(PO₄)₂SiO₄), which is the result of the first step in said method. The present invention also relates to the use of matrices that include the cement or the ceramic in the preparation of therapeutic agents for maxillofacial and oral surgery, orthopaedic applications and/or controlled release of drugs, and also in tissue and bone engineering as cell-growth substrate.