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PROCESSES AND APPARATUSES FOR THE PRODUCTION OF CRYSTALLINE ORGANIC MICROPARTICLE COMPOSITIONS BY MICRO-MILLING AND CRYSTALLIZATION ON MICRO-SEED AND THEIR USE
PROCESSES AND APPARATUSES FOR THE PRODUCTION OF CRYSTALLINE ORGANIC MICROPARTICLE COMPOSITIONS BY MICRO-MILLING AND CRYSTALLIZATION ON MICRO-SEED AND THEIR USE
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机译:通过微细粉碎和结晶化制备微晶态结晶态有机微颗粒组合物的方法和用途
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摘要
The present invention relates to a process, for the production of crystalline particles of an active organic compound The process includes the steps of generating a micro-seed by a wet-milling process and subjecting the micro-seed to a crystallization process. The resulting crystalline particles have a mean particle size of less than about 100 mum. The present invention also provides for a pharmaceutical composition which includes the crystalline particles produced by the method described herein and a pharmaceutically acceptable carrier.
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