NOVEL TRANSITION METAL COMPLEX WITH NITROGEN-CONTAINING HETEROCYCLIC LIGANDS AND PHOSPHINE LIGANDS, PREPARATION THEREOF AND USES IN CATALYSIS

摘要

The present invention concerns a novel transition metal complex having nitrogen-containing heterocyclic ligands and phosphine ligands, the preparation thereof and the uses thereof in asymmetric catalytic hydrogenation and hydrogen transfer. The transition metals in the complex are Ru, Rh, Ir, Pd, Pt, Co, Ni or Os, there is one nitrogen-containing heterocyclic ligand, and two monophosphine ligands or one diphosphine ligand. The complex is obtained at temperatures in the range of 0°C - 120°C through a reaction of transition metal compounds, a dinitrogen or mononitrogen ligand and a diphosphine or monophosphine ligand in an organic solvent for 0.5 to 20 hours. The complex is used for catalysed asymmetric transfer hydrogenation or asymmetric hydrogenation reactions, and is used in particular in ketones, esters, acetophenones and their derivatives where α is steric alkyl, in benzophenone and its derivatives, in β-N, N-dimethylamino-α acetophenone and its derivatives and in catalysed asymmetric hydrogenation reactions of other ketone compounds.