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RAPID MOLECULAR ASSAYS FOR SPECIFIC DETECTION AND QUANTITATION OF LOA LOA MICROFILAREMIA

机译：快速检测和定量 LOA LOI 微丝线虫病的定量分子检测

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摘要

A series of quantitative assays capable of quantifying Loa loa microfilaria burden from small-volume blood samples is provided. The present invention also provides methods of use of the quantitative assays to identify individuals at risk for encephalopathy due to antifilarial treatment, and also provides oligonucleotide primers used in the assay methods. 展开▼

机译：提供了一系列定量分析方法，能够定量分析小剂量血液样本中的 Loa loa 微丝虫病负担。本发明还提供了使用定量测定法来鉴定由于抗丝虫处理而处于患脑病风险的个体的方法，并且还提供了用于测定法的寡核苷酸引物。 展开▼

著录项

公开/公告号WO2012061283A1

专利类型

公开/公告日2012-05-10

原文格式PDF

申请/专利权人 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES;NUTMAN THOMAS B.;FINK DORAN;
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申请/专利号WO2011US58565

发明设计人 NUTMAN THOMAS B.;FINK DORAN;
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申请日2011-10-31

分类号C12Q1/68;

国家 WO

入库时间 2022-08-21 17:16:06

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