首页> 外国专利> BLOOD COLLECTION TUBE, METHOD FOR PRODUCING BLOOD COLLECTION TUBE, AND METHOD FOR PREPARING BLOOD SAMPLE

BLOOD COLLECTION TUBE, METHOD FOR PRODUCING BLOOD COLLECTION TUBE, AND METHOD FOR PREPARING BLOOD SAMPLE

机译:血液收集管,血液收集管的制造方法以及血液样品的制备方法

摘要

Provided is a blood collection tube for measuring a blood glucose level, with which high drug solubility in blood is achieved, a drug is easily dissolved even if the number of tumble-mixing operations is small, and an anticoagulant ability and an inhibitory effect on glycolysis can be reliably exhibited.The blood collection tube comprising a first drug which is obtained by adhering and drying a first drug solution containing an acid having an acid dissociation constant pKa of 3.7 ± 1.0 and a pH of 3.0 to 6.0 and a second drug obtained by adhering and drying a second drug solution containing at least an ethylenediamine tetraacetate salt onto the inner wall of a tube with a bottom, which is a constituent member of the blood collection tube, wherein at least one of the first and second drug solutions contains a fluoride salt in an amount of 0.2 to 3.0 mg in terms of NaF per milliliter of blood to be collected; and a method for producing the blood collection tube comprising a step of preparing the first drug solution and the second drug solution, a step of applying the first and second drug solutions to the inner wall of a tube with a bottom by spraying, and a step of drying the applied first and second drug solutions.
机译:提供了一种用于测量血糖水平的采血管,通过该采血管可以实现在血液中的高药物溶解性,即使滚筒混合操作的次数少,药物也易于溶解,并且具有抗凝血能力和对糖酵解的抑制作用。可以可靠地展示。该血液采集管包括:第一药物,其通过粘附和干燥包含酸解离常数pKa为3.7±1.0且pH为3.0至6.0的酸的第一药物溶液;和第二药物,该第二药物通过粘附并干燥第二药物而获得。在具有底部的管的内壁上至少包含乙二胺四乙酸盐的药物溶液,该底部是采血管的组成部分,其中第一和第二药物溶液中的至少一个包含一定量的氟化物盐。每毫升血液中以NaF计为0.2至3.0毫克;本发明涉及一种血液采集管的制造方法,其包括以下步骤:制备第一药液和第二药液;通过喷雾将第一药液和第二药液涂敷在具有底部的管的内壁上的步骤;干燥所施加的第一和第二药物溶液。

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