USE OF ETOMIDATE IN PREPARATION OF DRUG FOR PREVENTING OR TREATING POSTTRAUMATIC STRESS DISORDER

摘要

A use of etomidate in preparation of drugs for preventing or treating posttraumatic stress disorders. In an animal model, etomidate restores an elevated adrenal cortical hormone level caused by stress to a normal level, reverses the declined expression level of the adrenal cortical hormone receptors in cerebral regions such as hippocampus and aberrant hippocampal synaptic plasticity caused by stress, and alleviate anxiety and depression caused by chronic stress.