AMINO ACID COMPOSITION AND ITS USE FOR TREATING INTRAUTERINE FOETAL GROWTH RESTRICTION (IUGR) OR FOR PARENTERAL NUTRITION OF EXTREMELY PRE-TERM INFANTS

摘要

The invention relates to a composition for use in the treatment of foetal growth restriction (IUGR) or for parenteral nutrition of infants born extremely pre-term, in weeks 24 to 34 of pregnancy. The composition comprises a mixture of amino acids or their synthetic or modified amino acid analogues or substitutes, selected from the group of the following: isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, arginine, histidine, ornithine, glycine, alanine, proline, aspartate, asparagine, glutamate, glutamine, serine, tyrosine, taurine, hydroxyproline, citrulline, cysteine. The amino acids present in the solution are present at concentrations or in concentration ratios which correspond or come extremely close to the physiological amino acid concentrations or concentration ratios in the blood plasma of a healthy foetus in utero in weeks 24 to 34 of pregnancy.