METHODS TO IDENTIFY CHRONIC LYMPHOCYTIC LEUKEMIA DISEASE PROGRESSION

摘要

The present invention provides materials and methods related to CLL disease progression. The invention provides methods related to differential expression signatures, including distinguishing histological subtypes, progression patterns, poor survival patterns, and disease-free survival patterns. Antisense and sense miRNAs, kits, and other compositions, such as pharmaceutical formulations and combination therapies are also provided.