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TREATMENT AND PREVENTION OF BACTERIAL VAGINOSIS AND GARDNERELLA VAGINALIS INFECTIONS

机译：细菌性阴道炎和阴道加德纳菌感染的治疗和预防

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摘要

G. vaginalis infection, a major cause of bacterial vaginosis (BV), is associated with biofilm formation. The present invention relates to treatment of G. vaginalis infections and BV with DNase. DNase reduces biofilm formation and increases biofilm breakdown, both in a dose dependent manner. The present invention further relates to treating BV and G. vaginalis infections with a combination of DNase and an antibiotic known to treat these diseases.

机译： G。阴道感染是细菌性阴道病（BV）的主要原因，与生物膜形成有关。本发明涉及Ig的治疗。阴道炎和DNase BV。 DNase以剂量依赖性方式减少生物膜形成并增加生物膜分解。本发明进一步涉及治疗BV和I G。 DNase和已知可治疗这些疾病的抗生素联合感染阴道。 展开▼

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公开/公告号WO2012106264A3

专利类型

公开/公告日2012-09-20

原文格式PDF

申请/专利权人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;RATNER ADAM J.;HYMES SAUL;
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申请/专利号WO2012US23185

发明设计人 RATNER ADAM J.;HYMES SAUL;
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申请日2012-01-30

分类号A61K38/46;A61P31/04;

国家 WO

入库时间 2022-08-21 17:14:24

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