ANTIGENIC APPROACH TO THE DETECTION AND ISOLATION OF MICROPARTICLES ASSOCIATED WITH FETAL DNA

摘要

The present disclosure provides methods of quantifying and isolating microparticles of fetal from maternal bodily fluids such as cell free maternal plasma. Antibodies or combinations of antibodies that selectively bind fetal microparticles in maternal bodily fluid permit quantification by flow cytometry and isolation through flow cytometry based sorting and immunopurification.