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SYSTEM FOR AUTOMATING ANIMAL TESTING PROTOCOLS

机译:动物测试协议自动系统

摘要

In one aspect, the present invention provides a housing system for conducting high throughput animal experiments. The housing system includes a home cage, at least one rotatable turnstile enclosed by housing to form two or more isolation chambers, a means for animal identification, and one or more action stations functionally coupled to one or more isolation chambers. The turnstile includes a plurality of one or more separation members rotatable about a vertical axis, each isolation chamber bounded by one or more separation members. The action stations contain one or more devices facilitating completion of at least one animal-directed or experimenter-initiated action. In a preferred embodiment, the home cage is sufficiently sized to house a plurality of small animals, such as mice. Tunnel passageways may be connected to the home cage, including one or more tunnel passageways containing a rotatable turnstile. Additional embodiments include rotatable turnstiles, rotatable turnstile assemblies, and methods of conducting high throughput animal experiments using the devices and systems described herein.
机译:一方面,本发明提供了用于进行高通量动物实验的容纳系统。该容纳系统包括:一个家用笼,至少一个可旋转的旋转栅栏,该旋转栅栏被外壳包围以形成两个或多个隔离室;一种用于动物识别的装置;以及一个或多个在功能上耦合至一个或多个隔离室的作用站。旋转栅包括多个可绕竖直轴线旋转的一个或多个分离构件,每个隔离室由一个或多个分离构件界定。动作台包含一个或多个有助于完成至少一种动物指导或实验人员发起的动作的设备。在一个优选的实施方案中,家庭笼子的尺寸足以容纳许多小动物,例如小鼠。隧道通道可以连接到家庭笼,包括一个或多个包含可旋转的旋转门的隧道通道。其他实施方式包括可旋转的旋转门,可旋转的旋转门组件,以及使用本文所述的装置和系统进行高通量动物实验的方法。

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