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COMPOSITION FOR PREVENTING OR TREATING SJOGREN'S SYNDROME, BEHCET'S SYNDROME, ANKYLOSING SPONDYLITIS OR SYSTEMIC LUPUS ERYTHEMATOSUS COMPRISING EGCG AS AN ACTIVE INGREDIENT
COMPOSITION FOR PREVENTING OR TREATING SJOGREN'S SYNDROME, BEHCET'S SYNDROME, ANKYLOSING SPONDYLITIS OR SYSTEMIC LUPUS ERYTHEMATOSUS COMPRISING EGCG AS AN ACTIVE INGREDIENT
PURPOSE: A pharmaceutical composition containing EGCG(epigallocatechin gallate) is provided to suppress differentiation of cytotoxic Th17 cells and to prevent or treat Sjogren syndrome, Behcet syndrome, or lupus. CONSTITUTION: A composition for preventing or treating Sjogren syndrome, Behcet syndrome, or lupus contains EGCG(epigallocatechin gallate) compound or salt thereof as an active ingredient. The EGCG suppresses or reduces differentiation of undifferentiated T cells into Th17 cells. A method for activating regulatory T cells comprises a step of treating the EGCG compounds or salt thereof to the T cells(Treg) in vitro. A functional food for treating or preventing Sjogren syndrome, Behcet syndrome, or lupus contains the EGCG compound or salt thereof as an active ingredient. A composition for suppressing immunity contains the EGCG compounds or salt thereof as an active ingredient.
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