Inotropic agent or antiarrhythmic agent using M1 anti-muscarinic drug like Pirenzepine, telenzepine without cardiac toxicity with ionic binding complex of negatively charged gold nanoparticles and choline

摘要

PURPOSE: choline-gold nanoparticle compound includes Antimuscarinic drugs selectively only muscarine acetylcholinergic receptor to be blocked to combine. ;CONSTITUTION: cholinium ion-gold nanoparticle compound includes M1 Antimuscarinic drugs such as pirenzepine and Telenzepine, avoids side effect to heart. The compound inducing ion key distinguishes the intrinsic time by the gold nanoparticle of liquid relief advertisement one molecule of vortex. ;The 2012 of copyright KIPO submissions