MICROORGANISM WITH IMPROVED L-AMINO ACID PRODUCTIVITY AND A METHOD FOR PRODUCING THE L-AMINO ACIDS USING THE SAME

摘要

PURPOSE: A method for producing L-amino acids using E.coli is provided to supplement NADPH through NADP.;CONSTITUTION: An E.coli microorganism with improved L-amino acid prouctivity has enhanced NAD kinase activation and is transformed for inactivation of enzyme having an amino acid of sequence number 2. The NAD kinase activation is enhanced by copy increase, expression regulatory site substitution, modification, or genetic mutation. The L-amino acid is L-threonine or L-tryptopan. A method for producing L-amino acid comprises a step of culturing E.coli to a culture medium containing sucrose or glucose and a step of isolating L-amino acid from the culture.;COPYRIGHT KIPO 2012