PURPOSE: A biomarker used in serological diagnosis for Crohn's disease is provided to specifically react to serum from a patient with Crohn's disease. CONSTITUTION: A marker for diagnosing Crohn's disease is derived from Mycobacterium avium subsp. Paratuberculosis and contains PhoS2-2(Periplasmic phosphate-binding lipoprotein 2-2). A composition for diagnosing Crohn's disease contains the marker. The composition is fixed on a carrier or support to enhance rapidity and convenience of diagnosis. The support comprises a sphere type(bead), cylindrical type(test tube or well inside), and flat type(sheet, test strip). A kit for diagnosing Crohn's disease contains the marker.
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