METHOD OF PREDICTING SPOT FORMATION ON THE SKIN WITH THE USE OF SPOT SITE-ACCELERATING GENES AS INDICATION AND METHOD OF SCREENING INHIBITOR FOR SPOT FORMATION ON THE SKIN

摘要

is an object of the present invention to provide a skin test method for prognosis for skin spot formation . The method or mouse MCP-2 gene in the epidermis AKO12157 gene , FLJ21763 gene of human or rat under high stringency hybridization conditions are possible with respect to a polynucleotide or gene S74257 Mcp9, Mcp10, Isg15, Usp18, Oas12, Gbp2, Gtpi, Ifi47, Igtp, Tgtp, Sprr2A, Krt2-6b, Cdk5rap2, Mef2C, Gsta4, Osf2, Tnc, Igfbp6, Ppicap, MCP-6 or Mm.74656 if the expression of genes that are expressed in the hyperactivity compared to normal skin , spots form is characterized in that the determination as easy skin .