Extraction, crystallization method as well as 4-beds Eluent Swing Adsorptive Continuous Unit and their operation methods for the simultaneous production of ultra pure betulin and high pure betulinic acid from birch barks

摘要

present invention, the Republic of Korea, China, North America and Europe, such as latitude 34 ^o more region in the northern half of indigenous birch (birch bark) of the shell (outer bark) and endothelial (inner bark) a polar organic solvent (polar organic solvent) used in the production of the betulinic content (betulin content) 70 ~ 83% , betulinic acid (betulinic acid) content of 4-8% by weight of the crude extract (crude extract) and single (single) or mixed (mixed) polar solvent (polar solvent) used hayeoseo a purity of 95% or more by weight of the highly pure betulinic crystallization (crystallization) to describe the present, and the product crystallized from the purity of 99.5% or more ultra-high purity (ultra pure) betulinic and a purity of 95% or more by weight of high purity (high pure) betulinic acid (betulinic acid) can produce simultaneous Birch is from the bark of the ultra-high purity betulinic and simultaneous production of highly pure betulinic acid method and apparatus.