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PORPHYRIN-BASED COMPOUNDS FOR TUMOR IMAGING AND PHOTODYNAMIC THERAPY
PORPHYRIN-BASED COMPOUNDS FOR TUMOR IMAGING AND PHOTODYNAMIC THERAPY
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机译:卟啉基化合物在肿瘤成像和光动力疗法中的应用
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摘要
This invention describes a first report on the synthesis of certain 124 I-labelled photosensitizers related to chlorines and bacteriochlorins with long wavelength absorption in the range of 660-800 nm. In preliminary studies, these compounds show a great potential for tumor detection by positrom emission tomography (PET) and treatment by photodynamic therapy (PDT). The development of tumor imaging or improved photodynamic therapy agent(s) itself represent an important step, but a dual function agent (PET imaging and PDT) provides the potential for diagnostic body scan followed by targeted therapy.
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