Pharmaceutical composition for treating gastric ulcer and / or duodenal ulcers 12

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: there is offered a pharmaceutical composition for treating and/or preventing gastric and duodenal ulcer containing a proton pump inhibitor (PPI) and N-acetyl-5-methoxytriptamine (melatonin) in the following proportions: PPI - 10 mg - 30 mg; N-acetyl-5-methoxytriptamine (melatonin) - 2 mg - 8 mg; excipients - up to 100 mg with the PPI being presented by the compounds specified in a group: lansoprazole, rabeprazole, esomeprazole, pantoprazole The composition has been found to provide the efficacy equal or exceeding such ensured by common doses of the PPI with prolonged therapeutic action (i.e. specified PPI doses are single and daily).;EFFECT: pharmaceutical composition may be presented by a solid dosage form - tablets, film-coated tablets, softgel capsules, solid gel capsules, by a soft dosage form - rectal suppositories.;3 cl, 21 tbl