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APPLICATION OF CATIONIC SURFACTANTS FOR PROTECTION AGAINST TEETH EROSION

机译:阳离子表面活性剂在牙齿侵蚀防护中的应用

摘要

1. The use of cationic surfactant obtained by condensation of fatty acids and esterified dibasic amino acids, having the formula (1):! ! where! X- is a counterion derived from an inorganic or organic acid, preferably Br-, Cl- or HSO4 -, or an anion based on a phenolic compound; ! R1 represents a straight alkyl chain of an unsaturated fatty acid or hydroxy acid containing from 8 to 14 atoms, linked to the α-amino acid group by an amide bond; ! R2 is a straight or branched alkyl chain containing from 1 to 18 carbon atoms, or an aromatic group; ! R3 represents! ! !or ! ! where n lies in the range from 0 to 4,! as protective agents for protecting teeth from pathological erosion. ! 2. The use according to claim 1, characterized in that the cationic surfactant is used in the form of compositions for oral use, such as sweets, confectionery, tablets, lozenges, candies, chewing gums, jams, jellies, dragees or dry powder mixtures intended for dissolving to produce drinks. ! 3. The use according to claim 1 or 2, characterized in that the composition for oral administration is a chewing gum or lozenge. ! 4. The use according to claim 3, characterized in that the compound of formula (1) is contained in the composition in a concentration of from 0.001 to 5 wt.%, Preferably from 0.001 to 2 wt.%. !5. The use according to claim 1 or 2 by eating, chewing or sucking the composition. ! 6. The use according to claim 3, characterized in that the compound is an ethyl ester of lauroylarginine hydrochloride. ! 7. Composition for oral administration, such as weak
机译:1.通过将脂肪酸和酯化的二元氨基酸缩合而获得的阳离子表面活性剂,其具有式(1): !哪里! X-是衍生自无机或有机酸,优选Br-,Cl-或HSO4-的抗衡离子,或基于酚类化合物的阴离子。 ! R1表示通过酰胺键与α-氨基酸基连接的含有8至14个原子的不饱和脂肪酸或羟基酸的直链烷基链; ! R2是含有1至18个碳原子或芳族基团的直链或支链烷基链; ! R3代表! ! !要么 ! !其中n介于0到4之间!作为保护牙齿免受病理侵蚀的保护剂。 ! 2.根据权利要求1的用途,其特征在于阳离子表面活性剂以口服组合物的形式使用,例如糖果,糖食,片剂,锭剂,糖果,口香糖,果酱,果冻,糖衣杏仁或干粉混合物。用于溶解产生饮料。 ! 3.根据权利要求1或2的用途,其特征在于用于口服的组合物是口香糖或锭剂。 ! 4.根据权利要求3的用途,其特征在于在组合物中包含式(1)的化合物的浓度为0.001-5重量%,优选0.001-2重量%。 5。 3.根据权利要求1或2的用途,其通过食用,咀嚼或吮吸所述组合物。 ! 6.根据权利要求3的用途,其特征在于该化合物是月桂酰精氨酸盐酸盐的乙酯。 ! 7.用于口服给药的组合物,例如弱

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