METHOD FOR DETERMINING TYPE OF INFLAMMATORY RHEUMATIC DISEASE USING SYNOVIAL FLUID

摘要

1. The method of determining in vitro the type of inflammatory rheumatic disease, characterized in that they determine the presence or absence of Hdj2 protein in the synovial fluid at an early stage of the disease. ! 2. The method according to claim 1, characterized in that the rheumatoid disease is selected from the group comprising: rheumatoid arthritis, infectious or septic arthritis, arthritis in rheumatic diseases of the spine; arthritis in inflammatory bowel diseases, juvenile chronic arthritis, arthritis in inflammatory diseases of connective tissue; allergic arthritis; arthritis caused by metabolic diseases, gout, arthritis with endocrine disorders such as hyperthyroiditis, hypothyroiditis, hyperparathyroiditis, hypoparathyroiditis, diabetes mellitus, Cushing's syndrome, acromegaly, pheochromocytoma; arthritis with granulomatous diseases; arthritis for bleeding in the joints as a result of bleeding disorders, arthritis for diseases of the hematopoietic system, neoplastic arthritis, paraneoplastic arthritis, osteoarthritis, arthritis after damage; arthritis for diseases of articular cartilage, arthritis for neuropathies, arthritis for skin diseases, more specifically psoriatic arthropathy. ! 3. The method according to one of the preceding paragraphs, characterized in that the presence of the Hdj2 protein in the synovial fluid is determined by the immunological method. ! 4. The method according to claim 3, characterized in that the immunological detection method uses at least one antibody that specifically binds to the epitope of the Hdj2 protein. !5. The method according to claim 3, characterized in that the method is an ELISA. ! 6. The method according to claim 3, �