首页> 外国专利> METHOD OF VERIFYING DIAGNOSIS OF PHEOCHROMOCYTOMA AND/OR PARAGANGLIOMA IN PATIENTS WITH EARLIER DETECTED LEVEL OF DAILY CONJUGATED METANEPHRINE AND/OR CONJUGATED NORMETANEPHRINE EXCRETION, EXCEEDING UPPER NORM LIMIT

METHOD OF VERIFYING DIAGNOSIS OF PHEOCHROMOCYTOMA AND/OR PARAGANGLIOMA IN PATIENTS WITH EARLIER DETECTED LEVEL OF DAILY CONJUGATED METANEPHRINE AND/OR CONJUGATED NORMETANEPHRINE EXCRETION, EXCEEDING UPPER NORM LIMIT

机译:检验每日联合甲氨蝶呤和/或甲氨蝶呤分泌超标,超过正常上限的患者早期检测出的嗜铬细胞增多症和/或寄生虫病的方法

摘要

FIELD: medicine.;SUBSTANCE: in patients with earlier detected excess of upper norm limit of level of daily conjugated metanephrine and/or conjugated normetanephrine excretion level of daily excretion of conjugated metanephrine and/or conjugated normetanephrine is determined in sample of collected urine at the background of clonidine intake. Sample is positive if the level of daily excretion of conjugated normetanephrine and/or conjugated metanephrine in sample of collected urine is higher than upper norm limit. Claimed method of diagnosis verification possesses high sensitivity and specificity.;EFFECT: method application makes it possible to avoid carrying out unjustified surgery in patients with essential arterial hypertension and hormonally non-active formation of adrenal gland.
机译:领域:医学;研究对象:在较早检测到每日共轭间肾上腺素和/或共轭去甲肾上腺素排泄水平上限超出上限的患者中,在收集的尿液样本中测定共轭间肾上腺素和/或共轭去甲肾上腺素每日排泄水平可乐定摄入量的背景。如果收集的尿液样本中的共轭去甲肾上腺素和/或共轭去甲肾上腺素的每日排泄水平高于正常上限,则该样本为阳性。所要求的诊断验证方法具有很高的灵敏度和特异性。效果:该方法的应用使避免患有原发性高血压和荷尔蒙激素异常活跃的患者避免进行不合理的手术成为可能。

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