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METHOD FOR PREDICTION OF ANTIVIRAL THERAPY (AVT) EFFICACY IN CHRONIC HEPATITIS B (CHB)
METHOD FOR PREDICTION OF ANTIVIRAL THERAPY (AVT) EFFICACY IN CHRONIC HEPATITIS B (CHB)
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机译:预测慢性乙型肝炎(CHB)的抗病毒治疗(AVT)疗效的方法
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摘要
FIELD: medicine.;SUBSTANCE: for the purpose of prediction of a virusological reponse in the patients suffering chronic combined HBV/HCV-infection, the antiviral therapy of chronic hepatitis B is associated with measuring the blood serum TNF-α cytokine content prior to and during the therapy on the 4-5th week and on the 7-8th week. If the initial TNF-α cytokine content increased in 1.5 times and more on the 4-5th week of the therapy to be decreased in 1.5 times and more from the initial level on the 7-8th week of the therapy, a good efficacy of the prescribed therapy is predicted. If the initial increased in 1.5 times and less on the 4-5th week or the TNF-α value decreased in 1.5 times and less from the initial level on the 7-8th week of the therapy, the therapy is predicted to be ineffective.;EFFECT: method allows early prediction of the antiviral therapy effect in the 4-8th weeks from the beginning of the therapy.;2 dwg, 2 ex
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机译:领域:医学。物质:为了预测患有慢性HBV / HCV合并感染的患者的病毒学反应,慢性乙型肝炎的抗病毒治疗与在使用HBV / HCV之前和之后测量血清TNF-α细胞因子的含量有关在治疗期间的第4-5周和第7-8周。如果在治疗的第4-5周初始TNF-α细胞因子含量增加1.5倍或更多,而在治疗的第7-8 Sup>周则从初始水平降低1.5倍或更多。在该疗法中,可以预测处方疗法的良好疗效。如果在治疗的第4-5周初始剂量增加了1.5倍或更少,或者在治疗的7-8周时TNF-α值较初始水平降低了1.5倍或更少,则预示该疗法无效。效果:该方法可从治疗开始的4-8周内早期预测抗病毒治疗效果。2dwg,2 ex
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