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METHOD OF PREVENTION AND TREATMENT OF LIVER DISEASE WITH APPLICATION OF RECEPTOR A2B ANTAGONISTS

机译:应用受体A 2B 拮抗剂的肝病防治方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: group of inventions relates to field of medicine. Method of treatment and prevention of liver fibrosis includes peroral introduction to mammal of therapeutically efficient amount of antagonist of adenosine receptor A2B - 3-ethyl-1-propyl-8-(1-{[3-(trifluormethyl)phenyl]methyl}pyrazol-4-yl)-1,3,7-trihydropurine-2,6-dione. Method of reducing hepatotoxic side effects of chemical therapy or radiotherapy includes peroral introduction to mammal who underwent such treatment of therapeutically efficient amount of antagonist of adenosine receptor A2B - 3-ethyl-1-propyl-8-(1-{[3-(trifluormethyl)phenyl]methyl}pyrazol-4-yl) -1,3,7-trihydropurine-2,6-dione.;EFFECT: application of claimed group of inventions is efficient for prevention and treatment of liver diseases.;6 dwg, 21 ex
机译:技术领域:发明组与医学领域有关。治疗和预防肝纤维化的方法包括将治疗有效量的腺苷受体A 2B -3-乙基-1-丙基-8-(1-{[3-(三氟甲基)苯基]甲基}吡唑-4-基)-1,3,7-三氢嘌呤-2,6-二酮。减少化学疗法或放射疗法的肝毒性副作用的方法包括向哺乳动物经口引入经治疗有效量的腺苷受体A 2B -3-乙基-1-丙基-8-( 1-{[3-(三氟甲基)苯基]甲基}吡唑-4-基)-1,3,7-三氢嘌呤-2,6-二酮。效果:所要求保护的一组发明对预防和治疗糖尿病有效肝病; 6 dwg,21 ex

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