METHOD FOR LOCAL PROLONGED CHEMOTHERAPY OF LOCALLY ADVANCED NONRESECTABLE DIGESTIVE ADENOCARCINOMA

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to oncology, and may be used for local chemotherapy of locally advanced nonresectable digestive adenocarcinoma. For this purpose, a dosage form 1.0 ml containing 5-fluorouracil, water for injections, low-molecular polyethylene, emulsifier T-2, microcrystalline gelatine and olive oil in certain proportions is introduced into subcutaneous fat surrounding an organ, ligaments and under a serous membrane of the organs involved in the tumour. The single introduction shall not exceed 5.0 ml of the dosage form.;EFFECT: method promotes an evident prolonged antitumour effect through 7 weeks and reduced intoxication ensured by a lower dose of the preparation.;1 ex