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METHOD FOR ASSESSING CLINICAL EFFECTIVENESS IN PROSTATE CANCER

机译:前列腺癌临床疗效评估方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely oncology, and may be used in treating patients with generalised prostate cancer. That is ensured by androgen blockade. Three days later, AMACR, bcl-2, bmp-7 protein levels are measured by laser disorption time-of-flight mass spectrometry. It is followed by the intravenous introduction of the mixture of autoblood 150 ml and docetaxel 80 mg incubated at 37°C for 40 minutes. In 21 days, the same amount of said mixture is introduced to total amount of docetaxel 400 mg. Five introductions of the chemopreparations are prescribed. The protein levels are measured once again. Decreasing the levels in 3-5 times testifies to the clinical effectiveness, while decreasing the protein levels less than in 3 times shows no therapeutic effect.;EFFECT: method provides the adequate assessment of the clinical effectiveness in the given pathology consistent with an adequate approach.;2 ex
机译:技术领域本发明涉及医学,即肿瘤学,并且可以用于治疗广义前列腺癌患者。这是通过雄激素阻断来确保的。三天后,通过激光吸收飞行时间质谱法测量AMACR,bcl-2,bmp-7蛋白水平。随后静脉内引入自体血150毫升和多西他赛80毫克的混合物,在37°C下孵育40分钟。在21天内,将相同量的所述混合物引入到多西他赛的总量400mg中。规定了五种化学制备方法的介绍。再次测量蛋白质水平。降低3-5倍的水平证明了其临床有效性,而降低蛋白质的水平低于3倍则表明没有治疗效果。效果:该方法可根据适当的方法对给定病理学的临床有效性进行充分评估。; 2前

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