METHOD FOR MODIFICATION OF POLYPHENOL-CONTAINING HERBAL MATERIALS AND USE OF MODIFIED POLYPHENOL-CONTAINING HERBAL MATERIALS IN MEDICINE

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to pharmaceutical industry, particularly to a product containing an insulin response. A method for producing the product containing the insulin response involving mixing at least one polyphenol-containing herbal material specified in a group consisting of fruit, vegetables, tea, green tea, coffee, cocoa, chocolate and bark, and at least aqueous edible solvent for making the mixture; heating said mixture; adding at least one lactic acid bacilli strain specified in Lactobacillus plantarum, and optionally at least one protein source specified in a group including peptones, tryptones, yeast extracts and their combinations to said heated mixture for making the fermented mixture; and exposing said fermented mixture to the conditions suitable for fermentation for making the product reducing the insulin response, and optionally eliminating the Lactobacillus plantarum strain. The use of the product reducing the insulin response for preparing a composition for preventing or treating diabetes, metabolic syndrome, obesity and cardiovascular diseases.;EFFECT: product prepared by the method described above effectively reduces the insulin response.;15 cl, 7 dwg, 11 tbl