Apparatus and method for measuring water content and salt concentration in a multiphase fluid flow

• 1. 用于测量多相流体流的设备和方法 [P] . 中国专利： CN102472649A . 2012-05-23
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• 3. Apparatus and method for measuring water content and salt concentration in a multiphase fluid flow [P] . 美国专利： US8686745B2 . 2014-04-01

  机译： 用于测量多相流体流中的水含量和盐浓度的设备和方法

• 4. APPARATUS AND METHOD FOR MEASURING WATER CONTENT AND SALT CONCENTRATION IN A MULTIPHASE FLUID FLOW [P] . 美国专利： US2011006790A1 . 2011-01-13

  机译： 用于测量多相流中水和盐浓度的装置和方法

• 5. Apparatus and method for measuring water content and salt concentration in a multiphase fluid flow [P] . 英国专利： GB201006751D0 . 2010-06-09

  机译： 用于测量多相流体流中的水含量和盐浓度的设备和方法

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• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. Electromagnetic and Optical Methods for Measurements of Salt Concentration of Water [J] . Ф.A.Tengesdal ,B.L.Hauge ,L.E.Helseth . 电磁分析与应用期刊（英文） . 2014,第6期
• 3. Method of Predicting Water Content in Crude Oil Based on Measuring Range Automatic Switching [J] . 陈祥光 ,朱文博 ,赵军 . 北京理工大学学报：英文版 . 2010,第1期
• 4. A Method for Detection of Trace Concentrations of Underivatized Amino Acid in Hydrothermal Fluids by Ion-Pairing Reversed-Phase UPLC-ESI-QTOF-MS [J] . Cécile Konn ,Jorgen Magnér ,Jean-Luc Charlou . 美国分析化学（英文） . 2015,第4期
• 5. ISO 20242-测试应用的服务接口简介——用于测量和自动化系统中设备集成的一种新的国际标准 [C] . 许(王莹) ,黎晓东 ,张利萍 . 第3届制造业自动化与信息化学术交流会暨制造业自动化与网络化制造系统集成学术交流会 . 2004
• 6. 激光粒度仪用于气固两相流中粒度分布的测量方法研究 [A] . 何孟元 . 2017