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KRAS VARIANT AND TUMOR BIOLOGY

机译:克拉斯变异生物学与肿瘤生物学

摘要

PROBLEM TO BE SOLVED: To provide identification of matter controlling transcribed modules as a promising approach to discover specified and individualized therapeutic methods.SOLUTION: There are provided a method for identifying specimens to be tested having cancer-developing risk by determining the presence or absence of SNP, which is well known as a KRAS variant, in a KRAS oncogene, a method for predicting the crisis of cancer, and a method for predicting the response of specimens to be tested to chemical therapy/treatment. The disclosure relates to fields of cancer, reproductive health and molecular biology. There is provided a method for diagnosing specimens having cancer and deciding prognosis of the same by deciding the presence or absence of a genetic marker. Furthermore, there is provided a method for determining the response of specimens to be tested to the treatment by determining the presence or absence of a genetic marker.
机译:解决的问题:提供识别转录模块的物质的方法,作为发现特定和个性化治疗方法的有前途的方法。 SNP,在KRAS癌基因中是众所周知的KRAS变体,一种预测癌症危机的方法,以及一种预测待测标本对化学疗法/治疗反应的方法。本公开涉及癌症,生殖健康和分子生物学领域。提供了一种用于诊断患有癌症的标本并通过确定是否存在遗传标记来确定其预后的方法。此外,提供了一种通过确定是否存在遗传标志物来确定待测样品对治疗的反应的方法。

著录项

  • 公开/公告号JP2013212052A

    专利类型

  • 公开/公告日2013-10-17

    原文格式PDF

  • 申请/专利权人 YALE UNIV;

    申请/专利号JP20120082590

  • 发明设计人 WEIDHAAS JOANNE B;

    申请日2012-03-30

  • 分类号C12Q1/68;A61K31/4745;A61K31/282;A61K31/337;A61P35;A61K39/395;G01N33/50;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 17:02:37

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