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Useful substituted cyclodextrin derivatives as intermediates for producing the substance that is biologically active

机译:有用的取代环糊精衍生物作为生产生物活性物质的中间体

摘要

In contrast to the mixture which is not defined clearly available in the prior art procedures, the present invention, substituted cyclodextrins are particularly useful intermediates to generate carboxyalkyl cyclodextrins that are well-defined relates to derivatives. The present invention also relates to a preparation process thereof in the process a limited number. It can be oversulfated according to procedures standard in the art carboxyalkyl cyclodextrins defined these well, particularly degenerative joint disease part of its alkali salts Porisurufeto of these ( For example, it for the prevention, or show certain properties of the biologically active for connective tissue repair or cartilage repair and / or treatment of heparin-induced thrombocytopenia or osteoarthritis) is known. None [Selection Figure]
机译:与现有技术方法中没有明确定义的混合物相反,本发明中,取代的环糊精是特别有用的中间体,用于产生与衍生物明确定义的羧烷基环糊精。本发明还涉及其制备方法中的有限数量的方法。可以按照本领域标准的方法将其过硫酸化羧烷基环糊精将它们很好地定义,尤其是其碱金属盐Porisurufeto的退化性关节病部分(例如,它用于预防或显示出对结缔组织修复具有生物学活性的某些特性(软骨修复和/或肝素诱导的血小板减少症或骨关节炎的治疗)是已知的。无[选择图]

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