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It is by using a recursive algorithm, a system and method for correcting the phase mismatch error in DNA sequencing data
It is by using a recursive algorithm, a system and method for correcting the phase mismatch error in DNA sequencing data
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机译:它是通过使用递归算法,用于校正DNA测序数据中的相位失配误差的系统和方法
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摘要
An embodiment of a method for correcting an error associated with phasic synchrony of sequence data generated from a population of template molecules is described that comprises the steps of detecting signals generated in response to nucleotide species introduced during a sequencing reaction; generating an observed value for the signal detected from each of the nucleotide species; defining positive incorporation values and negative incorporation values from the observed values using a carry forward value and an incomplete extension value; and revising the carry forward value and the incomplete extension value using a noise value that is derived from observed values associated with the negative incorporation values.
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