MATERIAL AND METHOD FOR ALTERING IMMUNE RESPONSE TO EXOGENOUS AND ENDOGENOUS IMMUNOGEN, INCLUDING SYNGENEIC AND NON-SYNGENEIC CELL, TISSUE OR ORGAN

摘要

PROBLEM TO BE SOLVED: To provide a tissue engineering solution for achieving immunomodulation without reliance on chemicals or pharmaceuticals which compromise a patient's immune system.SOLUTION: The invention provides an implantable material for reducing an immune response or an inflammatory reaction, comprising a biocompatible matrix, and, anchored or embedded endothelial cells, endothelial-like cells, or analogs thereof, wherein the implantable material is provided to a recipient in an amount sufficient to reduce the immune response or inflammatory reaction in the recipient.