Compounds (cysteine-based lipopeptides) and compositions as TLR2 agonists for use in the treatment of infectious diseases, inflammation, respiratory diseases, etc.

摘要

The invention provides a novel class of compounds viz. generally lipopeptides like Pam3CSK4, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 2. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness a vaccine.