MORPHOGENETIC FACTOR TREATMENT OF CHRONIC RENAL FAILURE

摘要

PROBLEM TO BE SOLVED: To provide a treatment method and agent to be used for treatment of a mammal subject having a chronic renal failure, having a risk of chronic renal failure, or having need of renal replacement therapy.SOLUTION: The problem is solved by the treatment method provided herein, which includes the administration of specific protein or protein based thereon of osteogenic protein (OP)/bone morphogenetic protein (BMP) family of TGF-β superfamily; the administration of specific morphogenetic factors, inductive factors thereof, or corresponding morphogenetic factor receptor agonist; or transplanting of renal cell induced by using the morphogenetic factors. The useful morphogenetic factors are members of OP/BMP family proteins or proteins based thereon.