首页> 外国专利> Composition for prevention or treatment of cervical cancer comprising human papillomavirus variant and immunopotentiator

Composition for prevention or treatment of cervical cancer comprising human papillomavirus variant and immunopotentiator

机译:预防或治疗宫颈癌的组合物,其包含人乳头瘤病毒变体和免疫增强剂

摘要

A composition for preventing or treating cervical cancer comprising a human papillomavirus plasmodium and an immunity enhancer is provided. A fusion protein including a fusion polypeptide recombined to transform a 3D structure of E6 and E7, which are antigens against types 16 and 18 human papillomavirus (HPV), a signal peptide for secreting the fusion polypeptide outside the cells and an immunity enhancer peptide present in an individual is also provided. The fusion protein may be useful in treating HPV-triggered tumors by inducing an immune response specific to the antigens against the HPV types 16 and 18.
机译:提供了用于预防或治疗子宫颈癌的组合物,其包含人乳头瘤病毒疟原虫和免疫增强剂。融合蛋白,其包含重组以转化E6和E7的3D结构的融合多肽,所述E6和E7是针对16型和18型人乳头瘤病毒(HPV)的抗原,用于在细胞外分泌融合多肽的信号肽和存在于细胞中的免疫增强剂肽还提供了一个人。所述融合蛋白可通过诱导针对针对16和18型HPV的抗原的特异性免疫应答而可用于治疗HPV触发的肿瘤。

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