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Meganuclease variants that cleave DNA target sequences in the NANOG gene and uses thereof
Meganuclease variants that cleave DNA target sequences in the NANOG gene and uses thereof
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机译:切割NANOG基因中的DNA靶序列的大范围核酸酶变体及其用途
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摘要
Meganuclease variants cleaving DNA target sequences of the NANOG gene, vectors encoding such variants, and cells expressing them. Methods of using meganuclease variants recognizing NANOG gene sequences for modifying the NANOG gene sequence or for incorporating a gene of interest or therapeutic gene using the NANOG gene as a landing pad and a safe harbor locus.
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