The invention relates to a product which comprises a C4bp domain of a non-mammalian origin, particularly SEQ ID NO:1, or a variant thereof, and an antigen. The product is desirably in the form of a fusion protein. The chicken C4bp domain of SEQ ID NO:1 is also described. Antigens include monomeric antigens such as malarial and influenza antigens. The C4bp domain provides for assembly of multimeric complexes of the antigen, or mixtures thereof. The complexes are useful as vaccines.
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机译：本发明涉及包含非哺乳动物来源的C4bp结构域，特别是SEQ ID NO：1或其变体的产品，以及抗原。期望产物为融合蛋白的形式。还描述了SEQ ID NO：1的鸡C4bp结构域。抗原包括单体抗原，例如疟疾和流感抗原。 C4bp结构域提供了抗原的多聚体复合物或其混合物的组装。该复合物可用作疫苗。
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