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ChIPonChip data and gene integration of expression data analysis system and method

机译:表达芯片数据与基因整合的表达数据分析系统及方法

摘要

PPROBLEM TO BE SOLVED: To provide an integrated analysis system which is capable of efficiently narrowing down genes in accordance with a plurality of ChIP on Chip experiments and gene expression experiment results by integrating ChIP on Chip data and gene expression data as data easy to interpret per gene. PSOLUTION: An area identification part 31 determines binding states of transcription factors per gene, and a gene expression determination part 32 determines expression states per gene, and determination results are stored in a determination result storage device 33. A gene selection part 41 selects genes meeting a selection condition on the basis of the determination results stored in the determination result storage device 33 and sends a list of selected genes to a result integrating part 42 and a gene list storage device 43. The result integrating part 42 acquires transcription factor binding states and gene expression states from the determination result storage device 33 and merges these results and sends them to a control relation display part 44. The control relation display part 44 makes control relations between genes into a graph. A relevant gene extraction part 45 extracts relevant genes from a plurality of gene lists stored in the gene list storage device 43. PCOPYRIGHT: (C)2008,JPO&INPIT
机译:

要解决的问题:提供一种集成分析系统,该系统能够通过整合芯片上的ChIP数据和基因表达数据来轻松地根据多个芯片上的芯片实验和基因表达实验结果有效地缩小基因范围解释每个基因。

解决方案:区域识别部分31确定每个基因的转录因子的结合状态,基因表达确定部分32确定每个基因的表达状态,并将确定结果存储在确定结果存储装置33中。基因选择部分41基于确定结果存储装置33中存储的确定结果来选择满足选择条件的基因,并将选择的基因的列表发送到结果整合部42和基因清单存储装置43。结果整合部42获取转录因子结合来自确定结果存储装置33的状态和基因表达状态,并将这些结果合并并发送到控制关系显示部分44。控制关系显示部分44将基因之间的控制关系制成图表。相关基因提取部45从存储在基因列表存储装置43中的多个基因列表中提取相关基因。

版权所有:(C)2008,JPO&INPIT

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