TRANSFORMANT OF PLASMACYTOID DENDRITIC CELL PROPERTY LEUKEMIA CELL LINE AND USE OF THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a technique that reinforces a function that has already been provided and adds a new function to a plasmacytoid dendritic cell property leukemia cell line.;SOLUTION: A gene that codes a functional modulation protein CD80 that is a factor related to a costimulatory factor and/or a costimulatory signal is introduced to a plasmacytoid dendritic cell property leukemia cell line such as PMDC05 or the like, thereby the reinforcement of a function and the addition of a new function of the cell are made possible, and the reinforcement of an antigen-presenting capacity of a plasmacytoid dendritic cell property leukemia cell line, and the antigen presentation cell and a cytotoxic T-cell precursor cell are made to contact together, and the cytotoxic T-cell can be induced.;COPYRIGHT: (C)2013,JPO&INPIT